Clinical And Immunogenetic Aspects Of Recurrent Bronchitis In Children With Lymphatic-Hypoplastic Diathesis
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Jun 11, 2024
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Health, Republic, Uzbekistan, Ministry, Secondary, Higher, Education
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Abstract
Clinical and immunogenetic aspects of recurrent bronchitis in children with lymphatic-hypoplastic diathesis.” Monograph. Tashkent, 2024.-106 p. The monograph summarizes literature data and long-term research by the team of the Department of Pediatrics and Medical Genetics of Samarkand State Medical University, devoted to the issues of diagnosis, clinic, treatment tactics, rehabilitation of patients with recurrent bronchitis. The stages and methods of diagnostic search and treatment tactics for recurrent bronchitis in children are described in detail and consistently. The monograph is intended for pediatricians, surgeons, and general practitioners.
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Askarovna, S. O., Samievich, B. S., & Ashari , drg.Tontowi. (2024). Clinical And Immunogenetic Aspects Of Recurrent Bronchitis In Children With Lymphatic-Hypoplastic Diathesis. Umsida Press, 1 - 116. Retrieved from https://press.umsida.ac.id/index.php/umsidapress/article/view/1465
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References
1. Abdullaeva G.M. Therapy of recurrent bronchitis in young children against the background of perinatal cerebral pathology // Bulletin. Kazakh National Medical University No. 4. 2014. p.90-94
2. Akmalova G.M. and others. Genetic markers of predisposition to the development of relapses of the red plane of the oral mucosa // Experimental medicine, Kazan Medical Journal, 2016, volume 97, no.
3. pp.381-387. 3. Akparova A.Yu. and others. The role of the IL-4 and TNF-α cytokine genes in the development of predisposition to bronchial asthma and chronic obstructive pulmonary disease // Molecular genetic methods of research in medicine and biology. KarSMU. 2012. p.15-22.
4. Anokhina V.V., Neretina A.F., Kokoreva S.P. et al. Features of the course of acute respiratory diseases in children with respiratory diseases in children with an unfavorable premorbid background // Doctor. 2010, 27-30.
5. Antipkin Yu.G., Lapshin V.F. Recurrent bronchitis in children: modern issues of pathogenesis and diagnosis // Pediatrics No. 4 (43) 2017 p. 16
6. Akhverdieva T.B. Shuvalova Yu.V. Germasimova N.G. Features of the course and optimization of therapy for recurrent bronchitis in children // 2014 No. 6 p.56-66
7. Badyna O.S., Rovda Yu.I., et al. Sonometric parameters of the thymus gland in children in the first six months of life living in the Siberian region // Mother and Child in Kuzbass. 2014. p.153-158
8. Baike E.V., Urazov. O.I. Polymorphism of cytokine genes as a predisposition factor to the development of chronic otitis media // Pathological physiology and experimental therapy 2019 No. 1 p.4-14. 9. Balpanova G.T., Shortanbaev A.A., Talgatbekova D.Zh. Genetic markers of infectious diseases // Bulletin of KazNMU No. 4(1) 2013 p.100-102
10. Baranov A.A., Namozova-Baranova L.S. Federal clinical recommendations for providing medical care to children with acute bronchitis // M., 2015. 11 p.
11. Bakhodirova A.N., Alimova H.P., Rakhimova S.R. Principles for assessing the condition of children with broncho-obstructive syndrome in the emergency department // Bulletin of emergency medicine No. 3. Volume 12. 2019 p.26-27
12. Bodienkova G.M. The role of polymorphism and expression of individual cytokine genes in the formation of pathology // Modern advances. natural sciences. 2015. No. 1. c. 616-620
13. Boytsova E.A., Azimurodova G.O., Kosenkova T.V. Interleukin-4 Biological functions and clinical significance in the development of allergies // Preventive and clinical medicine No. 2(75) 2020 p.70-78
14. Vaganov P.D., Nikonova M.F., Yanovskaya et al. T-cell immunity in children with thymomegaly. Russian Medical Journal // 2017, 23 (6) p.298-302
15. Varyushina E.A. Pro-inflammatory cytokines in the regulation of inflammation and recovery processes // Abstract. St. Petersburg 2012. 16. Vozgoment O.V. On the role of lymphatic-hypoplastic diathesis in the fatal development of pathological processes in children and the criteria for its diagnosis // Difficult Patient No. 5, Volume 12. 2014 pp. 26-30
17. Volkov I. K. Differential diagnosis of broncho-obstructive syndrome in children // Emergency Medicine states. 2013. No.1. With. 125-128. 18. Volkova L.E., Rogalkaya S.V. Causes of perinatal death in children with thymus pathology // International Journal of Applied and Fundamental Research. 2013. No. 10-12. p.248-249
19. Vorobyova A.V. On the etiopathogenesis of acute bronchitis and bronchiolitis in children. Bulletin of new medical technologies // 2017. No. 4. P. 268-273.
20. Voropaeva Ya.V., Kuzmenko L.G. Prevalence of thymus diseases in children in the Russian Federation // Russian Bulletin of Perinatology and Pediatrics. 2012. No. 2. pp.99-103
21. Voropaeva Ya.V., Chibisov S.M. and others. Heliogeomagnetic situation in the first year of life of children with persistent thymic hyperplasia // The Journal of scientific articles “Health and Education Millennium”, 2015. No. 4 p. 262-265
22. Vychugzhanina E.Yu., Koledeva E.V. On the influence of thymic hyperplasia on the development of young children // Vyatka Medical Bulletin. 2015. No. 2. p.33-34
23. Geppe N.A., Kolosova N.G. Zaitseva O.V. and others. Diagnosis and therapy of bronchial asthma in preschool children. Place of use of inhaled glucocorticosteroids for bronchial asthma and croup // Russian Bulletin of Perinatology and Pediatrics. 2018. T. 63, No. 3. pp.124-132.
24. Gerasimova N. G., Akhverdieva T. B., Kondrashova Yu. V. et al. // Some aspects of the use of immunocorrective therapy for recurrent broncho-obstructive syndrome. Health and education in the 21st century. - 2016. No. 2. P. 568-570.
25. Guliev N.D., Ragimova N.D. Polymorphism of cytokine genes in non-congenital women with intrauterine infections \\ Russian Bulletin of Perinatology and Pediatrics, 2015 No. 6 p.42-47.
26. Guryeva, Larisa Lvovna Prediction of control of atopic bronchial asthma in childhood: abstract ... Doctor of Medical Sciences 01/14/08 Samara 2015
27. Danilko K.V., Bogdanova R.Z., Fatikhova A.I. and others. Polymorphism of cytokine genes in children with respiratory diseases // Modern problems of science and education. - 2015. -№6
28. Donetskova A.D., Nikonova M.F. and others. A new approach to the study of thymopoiesis in thymomegaly in children. Immunology. 2014; 4: p.204-208
29. Donetskova A.D., Nikonova M.F. and others. Features of T-lymphopoiesis in children with thymomegaly. Molecular diagnostics. Participating M: 2017 p.512-513
30. E.M. Kostina, B.A. Molotilov, O.A. Levashova et al. Study of polymorphism of the cytokine genes IL-4, IL-10, IL-17A and TNF-α in patients with infection-dependent bronchial asthma // Immunopathology. Infectology. 2013, No. 1, p. 53-58
31. Zaitseva O.V., Sitnikova E.P., Safina A.I. Comorbidity in pediatrics: is there a general solution // Effective pharmacotherapy. 2017. T. 3. No. 41. p.
32. Zaitseva O.V. Bronchitis in children, possibilities of herbal medicine // Russian Medical Journal. - 2013. -T. 21, no. 2. pp.96-102 33. Zykov M.V. et al. Study of the rs1800629 (G-308A) polymorphism of the TNF gene in patients with ST-segment elevation myocardial infarction. Russian Journal of Cardiology. http://dx.doi.org/10.15829/1560-4071-2014-10-13-18
34. Zykov M.V., Makeeva O.A. et al. Study of polymorphism rs 1800629 (G-308A) of the TNF gene in patients with myocardial infarction with ST segment elevation // Cardiogenetics, Russian Journal of Cardiology No. 10 (114) 2014
35. Kabbani M.S. Cell-mediated cytotoxicity (CD8 and CD16 phenotype) in the immune response (review) DOI:10.46742/2072-8840-2021-66-2-36-43,
36. Kaytmazova N.K. Dynamics of cytokine indicators in children with obstructive bronchitis when using immunomodulators in therapy http://dx.doi.org/10.26787/hydha-2686-6838-2019-21-12-39-44
37. Kazakova A.V., Uvarova E. .V., Limareva L.V. and others. Features of polymorphism of pro-inflammatory cytokine genes in girls predisposed to frequent respiratory diseases // Medical Genetics. Bulletin of the Russian State Medical University No. 6, 2019 p.61-66. 38. Kens E.V., Gnateiko O.Z., Lukyanenko N.S. Molecular genetic testing of single nucleotide polymorphism C-33T of the IL4 gene in children with repeated episodes of acute obstructive bronchitis // Medical Perspectives. 2018. p.67-71.
39. Kovalchuk L.V. Immunology: workshop: textbook. Manual / edited by. L.V. Kovalchuk, G.A. M.GEOTAR-Media 2014. p.174
40. Kosheleva I.V. The significance of serum levels and genetic characteristics of anti-inflammatory cytokines in patients with atopic dermatitis // Attending physician. 2019, No. 1, 53
42. Kuzmina L.P. Khotuleva A.G. Genetic polymorphism of anti-inflammatory cytokines in assessing the risk of development and prognosis of the course of occupational bronchopulmonary pathology. Collection of materials of the international scientific and practical conference. Moscow 2018 Volume 2 p.157-158
43. Lapshin V.F., Umanets T.R. Mucolytic therapy for children with recurrent bronchitis. Pathology pediatrics. 2014. 3(59):36-40; doi10.15574/pp.2014.59.36
44. Lastovka I.N. Features of the course of acute respiratory viral infections and meningococcal infection in young children with thymomegaly // Minsk, 2013. 21 p.
45. Lastovka I.N. Features of the course of acute respiratory infections in young children and thymomegaly // Protection of motherhood and childhood. 2013 p.20-24
46. Loginova N.P. Immunomorphological aspects of the structure of the thymus in children of the first year of life with congenital heart defects // Medical almanac. 2015. No. 2. p.112-116
47. Loskutov D.V., Khamitova R.Ya. Genetic component of chronic respiratory diseases among foundry workers // Hygiene and Sanitation. 2016.95. No. 7. p.623-626.
48. Lukashevich M.G., Surazakova T.N. Thymomegaly and the health status of children in the first year of life // Russian Bulletin of Perinatology and Pediatrics. 2016. T. 61, No. 4. P. 163.)
49. Maharramova S.G. Genetic polymorphism of cytokines in the development of respiratory diseases in children // DOI http: //dx.doi.org/10.5281/zenodo.1240483. Azerbaijan 2018 p.14-20.
50. Makarov S.Yu., Katilov A.V., Makarova O.I. Thymomegaly is a shadow of the past in the clinical practice of the present. LOOK FAHIVTSIA p.5-10 8(45)2015
51. Malanicheva T.G., Mozhgina S.S. and others. Local cytokine profile and cytological status in children with community-acquired pneumonia occurring against the background of reduced body resistance // Russian Bulletin of Perinotology and Pediatrics 2017: 62: (5) p. 139-143
52. Mirmanova N.A. Association of genetic polymorphism of the TNFα gene (G-308) with the formation of severe and complicated forms of influenza in children // Chita State Medical Academy Chita. Volume 5, No. 4 2013 p.30-34.
53. Moshchich A.P., Kalinichenko N.A. Rational correction of lymphatic-hypoplastic diathesis in the practice of a family doctor // Medicine of Ukraine No. 9-10. P.36-39. 2017
54. Mudrak D.A., Navolokin N.A. and others. Histological signs of enlargement of the thymus gland // Journal of Anatomy and Histology. 2020; 9(2): 46-52. doi: 10.18499/2225-7357-2020-9-2-46-52 9(2) pp.46-52.
55. Muhammadieva G.F., Kutlina T.G. and others. The role of polymorphic variants of TNF-α genes in the development of occupational bronchial asthma // Human Ecology No. 10. 2017. p. 34-38.
56. Minyailova N.N., Rovda Yu.I., Zinchuk S.F., Klimanova A.E., Stroeva V.P., Chernykh N.S. Aspects of the thymus gland in childhood (Part V). Hormonal and morphological relationships of the thymus with the neuroendocrine system and, in particular, with somatotropic hormone and insulin-like growth factor //Mother and Child in Kuzbass. 2022. No. 1(88). p.11-20.
57. Nasonov E.L. The role of interleukin 1β in the development of human diseases. Scientific and practical rheumatology. Moscow - 2018 No. 4 p.19-27.
58. Nevinsky A.B., Kramar L.V. and others. Modern approaches to the treatment and diagnosis of obstructive bronchitis in children // Medicine Bulletin 2015. No. 3 p. 46-47
59. Nesterenko Z.V. Recurrent bronchitis as a clinical variant of functional changes in the respiratory system in children // Pediatrician. - 2017. T.8-No.5 p.44-48.
60. Nesterenko, Z. V. Features of respiratory diseases in children with connective tissue dysplasia // Z. V. Nesterenko, A. A. Gritsai. Kharkov: 2014. 205 p.
61. Nikonova M.F. Vaganov P.D., Donetskova A.D. and others. The effect of tactivin therapy on T-lymphopoiesis in thymomegaly in young children with acute obstructive bronchitis // Russian Medical Journal 2017.p.18-20
62. Ovsyannikov D.Yu., Kravchuk D.A., Bolibok A.M. and others. Bronchial asthma is a difficult diagnosis in pediatrics // Clinical and emergency pediatrics 2016; 2: p.18-29.
63. Shaiderova I.G. Electromechanical activity of the heart and intracardiac hemodynamics in various forms of acute and recurrent bronchial pathology // Bulletin of Science and Practice. 2020. T. 6. No. 4. pp.112-117. https://doi.org/10.33619/2414-2948/53/13
64. Pavlenko V.A., Berezhansky P.V. Melnikova I.M. et al. Features of autonomic regulation in young children who have suffered acute obstructive bronchitis // Pulmonology of childhood: problems and solutions / ed. Yu.L Mizernitsky, A.D Tsaregorodtseva M. 2012. 254 p.
65. Pavlovskaya L.V., Boraeva T.T. Recurrent obstructive bronchitis as a risk factor for the development of bronchial asthma. Vladikavkaz Medical and Biological Bulletin. 2014; p78-82.
66. Pikuza O.I., Rizvanova F.F., Generalova E.V., Kravtsova O.A. Polymorphism of pro- and anti-inflammatory cytokine genes and acute bronchitis in children // Russian Bulletin of Perinatology and Pediatrics, 2017. No. 5. pp.136-138.
67. Pobedinskaya N.S., Ryvkin A.I., Glazova T.G., Reshetova T.G. Mechanisms of formation of high cough readiness in children with recurrent bronchitis // Pediatrics No. 2 (42) 2016 p.84-87.
68. Puzyreva L.V., Safonov A.D., Mordyk A.V. Respiratory diseases in HIV infection (REVIEW) // Journal of Infectology, Volume 8, No. 3., 2016. pp. 17-24.
69. Raisky D.V., Dzhumagaziev A.A., et al. Epidemiological features of acute bronchitis in Astrakhan children from 0 to 5 years of age from 2002 to 2012. Modern science and education // International scientific and practical conference. 2013 July 31, p.22-25
70. Rizvanova F.F., Pikuza O.I., Generalova E.V., Fayzullina R.A., Kravtsova O.A. Gene polymorphism and community-acquired pneumonia in children // Practical Medicine. 2018 Vol. 16, No. 8, pp. 70-73).
71. Rovda Yu.I., Minyailova N.N. and others. Aspects of the thymus gland (thymus) in childhood (part II) //Mother and Child in Kuzbass. 2021. No. 1(84). c. 4-23.
72. Rovda Yu.I., Vedernikova A.V., Minyailova N.N., Shabaldin A.V., Shmakova O.V., Chernykh N.S., Stroeva V.P. Aspects of the thymus gland in childhood (Part IV). Thymus and COVID-19 //Mother and Child in Kuzbass. 2021. No. 4(87). p.17-26
73. Rovda Yu.I., Shmulevich S.A., Shabaldin A.V. and others. Clinical and immunological characteristics of children in follow-up after surgery for congenital heart disease combined with forced thymusectomy // Pediatrics 2018. T. 97, No. 4. p. 50-58
74. Romanova E.N., Govorin A.V. Genetic polymorphism of TNF-a, IL-10, eNOS in patients with influenza A // H 1N1 complicated by pneumonia // Russia 2013. No. 3. With. 58-61.
75. Romantsev M.G., Melnikova I.Yu. and others. Respiratory diseases in frequently ill children // Doctor's Desk Reference. M.: GEOTAR-Med; 2017. 160.p.
76. Rubanenko O.A. Polymorphism of the genes interleukin 6, interleukin 10, superoxide dismutase and angiotensin converting enzyme and the risk of atrial fibrillation after cardiac surgery // Russian Cardiology No. 10 (138) 2016. pp. 37-42.
77. Rudenko K.A., Tuguz A.R. etc. The influence of polymorphism of the genes Il-17 (G197/197A), TNF-α (G308/308A), IL-6 (C174G) The influence of polymorphism of the genes IL-17 (G197/197A), TNF-α (G308 / 308A) , IL-6 (C174G) on spontaneous and in vitro stimulated production of the main proinflammatory cytokines in bronchial asthma // Immunology No. 2. 2014. p.92-94.
78. Savenkova N.D., Dzhumagaziev A.A., Bezrukova D.A., Raisky D.V. Markers of transient and persistent phenotypes of bronchial obstruction syndrome in children // DOI: 10.31550/1727-2378-2019-160-5-11-14
79. Savenkova N.D., Dzhumagaziev A.A., et al. Recurrent bronchitis in children: state of the problem // Astrakhan Medical Journal. 2014. No. 1. p.29-37.
80. Savenkova N.D., Dzhumangaziev A.A., Bezrukova D.A. Clinical and prognostic significance of broncho-obstructive syndrome phenotypes in the development of bronchial asthma in children // Astrakhan Medical Journal No. 2, 2019. pp. 51-59.
81. Samorodnova E.A., Fayzullina R.A. and others. Pathogenetic significance of membrane and metabolic disorders in bronchitis in children // DOI: 10.31550/1727-2378-2021-20-10-18-24
82. Sartaeva G.Sh., Iseva A.G. and others. The special role of tumor necrosis factor-alpha in the anti-tuberculosis response. Bulletin of KazNMU No. 4. 2018 p.69-73
83. Seliverstova E.N. Sergienko D.F., Bashkina. O.A. Clinical, diagnostic and prognostic significance of the IL-4 gene in the recurrent course of bronchial obstruction syndrome in children // Astrakhan Medical Journal No. 2, 2019 p.59-66.
84. Sereda E.V. Etiology and innovative approaches in the treatment of acute and chronic infectious and inflammatory bronchopulmonary diseases in children // Issues of modern pediatrics. -2011. Volume 10, No. 3. p.124-130.
85. Silantyeva I.V., Rovda Yu.I. and others. Sonometric parameters of the thymus gland in healthy and sick children of the first two years of life // Siberian Medical Journal. 2012. T. 27, No. 1. p. 103-106.)
86. Simbirtsev A.S. Immunopharmacological aspects of the cytokine system // Bulletin of Siberian Medicine // 2019 No. 1 p.84-95.
87. Simbirtsev A.S. Cytokines in the pathogenesis of human infectious diseases. // Medical academic journal 2013 No. 3 p. 18-41.
88. Smirnova A.Yu. Gnoevykh V.V. and others. Genetic aspects of multifactorial broncho-obstructive diseases // Ulyanovsk Medical and Biological Journal No. 1. 2014. p.8-17.
89. Smiyan A.I., Romanova T.A. and co-author. Features of the population composition of peripheral blood lymphocytes and immunoglobulins in children with acute obstructive bronchitis against the background of thymomegaly // Scientific bulletins of BelSU. Series Medicine Pharmacy 2014 No. 11 (182). p.37-41
90. Sorokman T.V., Sokolnik S.V., et al. Features of the course of acute respiratory viral infections in young children with thymomegaly // Child's Health 2016. No. 1. P. 34-38
91. Stashkevich D.S. Topical issues of immunology: cytokine system, biological significance, genetic polymorphism, determination methods // Textbook. Chelyabinsk 2016. 82 p.
92. Tatochenko V.K. Respiratory diseases in children: V.K. Tatochenko. Medicine, 2012. p.480.
93. Tatochenko V.K. Respiratory diseases in children: A practical guide. 2019.p.300
94. Trushina E.Yu., Kostina E.M., Molotilov B.A., Tipikin V.A. Baranova N.I. The role of cytokines IL-4, IL-6, IL-8, IL-10 in the immunopathogenesis of chronic obstructive pulmonary disease // Medical Immunology. 2019. T. 21. No. 1. c.89-98
95. Trushina E.Yu., Kostina E.M., Baranova N.I., Tipikin V.A. The role of cytokines as molecular markers of inflammation in non-allergic bronchial asthma // Modern problems of science and education. 2018. No. 4
96. Uzakbaev K. A. Acute bronchopulmonary pathology in children with congenital heart defects // International scientific and practical conference. Bishkek, 2016. pp. 89-90.
97. Fayzieva U.G. Features of the IL-1 and IL-4 genes in community-acquired pneumonia in children. Eurasian Bulletin of Pediatrics 3(10) 2021 p.40-43
98. Furman E.G., Mazunina E.S., Boytsova E.V., Ovsyannikov D.Yu. Prolonged bacterial bronchitis in children is a “new” “old” disease. Pediatrics. 2017; 96(2): pp.136-144.
99. Khaitov R.M. Immunology: textbook for universities / R.M. Khaitov. -2nd ed. processed additional GEOTAR-Media 2013. 521 p.
100. Kholodova I.N., Zakharova I.N. Returning to the past, or let's talk about the human constitution. Concilium Modicum. Pediatrics. 2016; 1: p.20-23.
101. Khotko E.A., Taganovich A.D. Polymorphism of receptor genes and their ligands in chronic obstructive pulmonary disease // Medical Journal. Belarus 2016 No. 3. pp. 36-42.
102. Chemodanov V.V., Krasnova E.E., Moshkova A.V. Features of bronchitis in combination with various pathologies in young children // Attending physician. 2021; 1 (24): pp.16-19.
103. Chirkova N.V., Baldina N.S., Dulkin L.A. Features of the course of recurrent obstructive bronchitis and community-acquired pneumonia in children with gastroesophageal reflux // Pediatrics (Appendix to the journal). 2017; 3: pp.101–104.
104. Churina E.G. Urazova O.I., Novitsky V.V. et al., Functional polymorphism of pro-inflammatory cytokine genes in pulmonary tuberculosis // Medical Immunology 2019 T. 21, No. 1, pp. 149-156
105. Shabalov N.P., Arsentiev V.G., Ivanova N.A. and others. Age-specific constitutional anomalies and diathesis. Pediatrics 2016; 2: pp.82-85.
106. Shamsiev A.M., Yusupov Sh.A., Mukhamadieva L.A., Yuldashev B.A. Features of changes in immunological parameters in children with chronic bronchitis. Scientific and practical journal // Bulletin of Nankov Doslidzheni” Ternopil No. 4 (85) 2016 p. 26-29.
107. Shamsiev A.M., Yusupov Sh.A., Mukhamadieva L.A., Yuldashev B.A. The state of the immune status in children with chronic bronchitis. Periodic information and analytical journal of the Chelyabinsk Regional Children's Clinical Hospital “Pediatric Bulletin of the Southern Urals” 2017, No. 1 p. 84-89.
108. Shields M.D., Doherty G.M. Chronic cough in children // Clinical and emergency pediatrics. 2015; 1: p.11-20.
109. Shuvalova Yu.V. Clinical and laboratory effectiveness of polyoxidonium in complex therapy of recurrent bronchial obstruction syndrome in children // Modern problems of science and education. 2013. No. 2. www.science-education.ru/ 108-8968.
110. Shcherbak V.A. Diathesis and constitutional anomalies in children //Siberian Medical Education 2014. 3. p.75-79.
111. Yakovenko M.P. Morbidity of children born with low and extremely low body weight with developed bronchopulmonary dysplasia // Attending physician - 2017. No. 11. P. 52-56.
112. Yakubova Z.Kh., Olimova K.S., Abdullaeva N.Sh. The role of thymomegaly in the formation of the health status of young children // Healthcare of Tajikistan. 2015. No. 1. P. 85-89
113. Yarilin A.A., Donetskova A.D. T cells are recent emigrants from the thymus. Immunology. 2012; 33 (6): 326-34.
114. Yarovaya Yu. A., Lozovskaya M. E., Vasilyeva E. B. et al. Constitutional features in children with tuberculosis infection // Tuberculosis and Lung Diseases. DOI: 10.21292/2075-1230-2017-95-4¬ 20-25
115. Al-Mohaya M.A., Al-Harthi F., Arfin M., Al-Asmari A. TNF-α, TNF-β and IL-10 gene polymorphism and association with oral lichen planus risk in Saudi patients. J. Appl. Oral Sci.2015; 23(3):295-301
116. Arsanova H.I., Kasymova Y.B., Bashkina O.A. Recurrent bronchitis in children:state of the problem. Archiveseuromedica 2018. Vol.8 No. 2. pp.67-68.
117. Ayhan G, Tas D, Yilmaz I, Okutan O, Demirer E, Ayten O, Kartaloglu Z. Relation between inflammatory cytokine levels in serum and bronchoalveolar lavage fluid and gene polymorphism in young adult patients with bronchiectasis. J Thorac Dis 2014;6(6):684-693. doi: 10.3978/j.issn.2072-1439.2014.04.14
118. Babusikova E. [et al.] Association of Gene Polymorphisms in Interleukin 6 in Infantile Bronchial Asthma. Subscribe to this journal July 2017. p.381-386
119. Bohmwald K, Gálvez NS, Canedo-Marroquín G, Pizarro-Ortega MS, Andrade-Parra C, Gómez-Santander F and Kalergis AM (2019). 10: 452. DOI: 10.3389/fimmu.2019.00452
120. Chkhartishvili E. Thymomegaly and recurrent disease episodes in childrrin ESPID 2018. May 28 -Jun 2. https:// www. Morressier.com/article/thymomegaly-recurrent -episodes-children/ ad 774e0d462b80296ca6d06
121. Cowan J.E., Takahama Y. et al. Postnatal involution and counter-involution of the thymus. Front Immunol. 897. DOI: 10.3389/fimmu.2020.00897
122. Dawid S. [et al.] The signifcace of IL-1β+3953 C>T, IL-6 174 G>C and 696 G>A, TNF-α-308 G>A gene polymorphisms and 86 bp variable number tandem repeats et polymorphism of IL-1RN bronchopulmonary dysplasia in infantis born before 32 weeks of gestation /Cent Eur J Immunol. 2017: 42(3): p.287-293
123. Dinarello C.A. Overview of the IL-1 family in innate inflammation and acquired immunity// Immunol Rev. 2018 January;281(1): 8-27/ doi:10.1111/imr.12621.
124. Furkat Shamsiev [et.al] TNFα polymorphism (-308G>A) in children with chronic bronchitis// European Journal of Molecular et Clinical Medicine ISSN 2515-8260 Volume 7, Issue 2, pp. 2515-2520. 2020
125. Rincon M. et al., Role of IL-6 in Asthma and Other Inflammatory Pulmonary Diseases. Int J Biol Sci 2012; 8(9):1281-1290. doi:10.7150/ijbs.4874. Available from https:// www.ijbs.com / v 08 p.1281.htm
126. Gandhi F Pavon-Romero [at.al]. Single nucleotide polymorphisms in TNF are associated with susceptibility to aspirin-exacerbated respiratory disease but not to cytokine levels: a study in Mexican mestizo population. Biomark. Med 2017 11(12) 1047-1055
127. Gul K.A., Sonerud T, Fjærli H.O., Nakstad B, Abrahamsen T.G, Inchley C.S. Thymus activity measured by T-cell receptor excision circles in patients with different severities of respiratory syncytial virus infection BMCInfectDis. 2017; 17: 18. DOI:10.1186/s12879-016-2148-0
128. Haiyan Mu, Qingqing Zheng. IL-10-1082 A/G polymorphism is related with the risk and clinical characteristics of acute kidney injury: a case-control study. BMC Nephrology 2021. pp.1-6
129. Henan Madani. Hanaa I. Rady. Association of cytokine genes polymorphisms and the response to corticosteroid therapy in children with idiopathic nephrotic syndrome: A pilot study in Egypt/ International Research Journal of Medicine and Medical Sciences Vol.2(4), pp. 84-90, December 2014
130. Huang H, Nie W, Qian J [at al.] Effects of TNF-α Polymorphisms on Asthma. Esmon Publicidad.J Investig Allergol Clin Immunol 2014; Vol. 24(6): 406-417
131. HuGE Navigator (2013). Available at: http://www. Huge navigator. net/HuGE Navigator/ gene Prospector (accessed June 2013).
132. Hsu H.J., Yang Y.H., Shieh T.Y. et al. Role of cytokine gene (interferon-y, transformimg growth factor-β1, tumor necrosis factor-α, interleukin-6, and interleukin-10) polymorphismus in the risk of oral precancerous lesions in Taiwanese. Kaohsiung J. Med. Sci. 2014; 30 (11): 551-558
133. Interleukin-6 gene –174 G>C polymorphism and chronic obstructive pulmonary disease risk: a meta-analysis / X. M. Xie [et al.] // Genetics and Molecular Researc. - 2015.- Vol. 14, № 3. P. 8516-8525. 2015. №3 с.46-47
134. Ivanova N. A. Recurrent bronchial obstruction and asthma in children during the first five years of life. Russian Bulletin of Prenotology and Pediatrics 2016; (in Russ). DOI: 10.21508/1027-4065-2016-61-5-64-69
135. Ji-Hong Zhang, Mei Zhang, Ya-Nan Wang Correlation between IL-4 and IL-13 gene polymorphisms and asthma in Uygur children in Xinjiang DOI:10.3892/etm.2018.7096 pp.1374-1382.2019
136. Jin X., Wang J., Zhu L. [et al.] Association between -308 G/A polymorphism in TNF-α gene and lichen planus: a meta- analysis. J. Dermatol. Sci. 2012; 68; 127-134.
137. Jiang P, Yue Y-X, Hong Y, Xie Y, Gao X, Gu C-K, Hao H-J, Qin Y, Ding X-J, Song M, Li H-F and Zhang X (2018) IL-4Rα Polymorphism Is Associated With Myasthenia Gravis in Chinese Han Population. Front. Neurol. 9:529. doi: 10.3389/fneur.2018.00529
138. Kellogg C, Equills O. The role of the thymus in COVID-19 disease severity: implications for antibody treatment and immunization. Hum Vaccin Immunother. 2020.1-6. DOI: 10.1080/21645515.2020.1818519.
139. Kuzmenko L.G., Kiseleva N. M. Contemporary on the role of thymus in living organisms and its participation in the vaccinal process in children of young age. Clinical Pathophysiology. 2016:3(22): 104-114
140. Kuzmenko L.G., Smyslova Z.V, Kiseleva N.M, Bystrova O.V, Agarval R.K. To the question of the thymus, associated terminology, and health status of children with a large thymus. J of Scientific Articles Health and Education in the Education in the XXI Century. 2015; 17(4): 97-107.
141. Kurtukov E.A., RaginoYu.I. Potential biochemical marker sof chronic bronchitis. Bulletin of Siberian Medicine. 2021; 20 (2): 148–159. https://doi.org/10.20538/1682-0363-2021-2-148-159.
142. Lu R., Zhang J., Sun W. et al. Inflammation-related cytokines in oral lichen planus: an overview. J. Oral Pathol. Med. 2015; 44: 1-14
143. Luciano B Silva, Alexaandrino P [et al.] // The role of TNFα as a Proinflammatory cytokine in pathological processes. The Open Dentistry Journal.DOI: 10.2174/1874210601913010332, 2019, 13, 332-338
144. Lukashevich M.G., Surazakova T.N. Thymomegaly and the state of health of children in the first year of life. Russian Bulletin of perinatology and pediatrics. 2016; 61(4): 163.
145. Mayyada F Darweesh [at ol.]. The impact of genetic variation at TNF- α 308G/A on their serum production and severity of asthma disease// Journal of Physics 2019 pp.1-8
146. María Luisa Reigada-Rivera, Catalina Sanz Lozano [et ol.]. Polymorphisms in Human IL4, IL10, and TNF Genes Are Associated with an Increased Risk of Developing NSAID-Exacerbated Respiratory Disease Genes 2022, 13, 605. https://doi.org/10.3390/genes13040605 h
147. Mizernitsky Yu.L. Pathogenetic rationale for the use of montelukast (Singlon) in acute respiratory viral infections with broncho-obstructive syndrome in children of early and preschool age. Ros Vestn Perinatoli Pediatr 2020; 65:(6): 129-132 (inRuss).
148. Nataliia Lukianenko [at.al] Finding a molecular genetic marker for the incidence of recurrent episodes of acute obstructive bronchitis in children// Journal of medicine and life. Pp695-699. 2021
149. Nesterenko Z.V. Recurrent bronchitis as a phenotypic variant of acute bronchitis in children. Ukraїnski jmedichnij vіsnik 2012; 15: p.121-123.
150. Onur Ismi [et. al]. TNF-α and IL-1β Cytokine gene polymorphism in patients with nasal polyposis. Turk arch Otorhinolaryngology 2017: pp.51-55
151. Patwari P.P. [et al.] Interleukin-1 receptor antagonist intron 2 variable number of tandem repeats polymorphism and respiratory failure in children with community-acquired pneumonia // Pediatr. Crit Care Med. 2008. Vol.9. №6 pp.553-559.
152. Pavón-Romero, G.F.; Reséndiz-Hernández, J.M. [et ol.]. Single nucleotide polymorphisms in TNF are associated with susceptibility to aspirin-exacerbated respiratory disease but not to cytokine levels: A study in Mexican mestizo population. Biomark. Med. 2017, 11, 1047–1055. [CrossRef] [PubMed]
153. Polyakov V.V., Senatorova A.S. The clinical significance of endothelial dysfunction in children with recurrent obstructive bronchitis and bronchial asthma. Mezhdunarodnij meditsinskij zhurnal 2012; 2: 32-36.
154. Petrova A.I., GaymolenkoI.N., Tereshkov P.P. Clinical and immunological markers of acute obstructive bronchitis in preschool children. Siberian medical review. 2019;(6):32-36. (In= Russ.) https://doi.org/10.20333/2500136-2019-6-32-36.
155. Qi Xiao [at.al] Three polymorphisms of tumor necrosis factor-alpha and hepatitis B virus related hepatocellular carcinoma. Medicine 2016 (95:50 (e5609).
156. Rakhmanova L.K., Savenkova N.D., Iskandarova I.R. Immune-hematological risks of progression of chronic kidney disease in children with lymphatic diathesis. // journal of Xi`an University, Natural Science Edition. Vol. 16. Pp297-311. 2018
157. Resul Kahraman [at al.] Evaluation of TNF alpha G308A promoter gene polymorphism and serum TNF alpha levels in patients with inflammatory bowel disease in Turkish population. Medicine Science 2019: 8(4): 1006-10.
158. Sanchez-Dominguez [et al.] (2014) The Tumor Necrosis Factor α (-308 A/G) Polymorphism Is Associated with Cystic Fibrosis in Mexican Patients. 9(3): e90945. https://doi.org/10.1371/journal.pone.0090945
159. Savenkova N.D., Dzhumangaziev A.A. et al. Rehabilitation of children with recurrent bronchitis using a nov-invasive apparatus of microwave exposure. [Human Ecology]. 2017, 12, pp. 53-58.
160. Schett G, Dayer J-M, Manger B. Interleukin-1 function and role in rheumatic disease. Nat Rev Rheumatol. 2016 Jan;12(1):14-24. doi: 10.1038/nrrheum.2016.166
161. Shang H., Cao X.L., Wan Y.J., Meng J., Guo L.H IL-4 Gene Polymorphism May Contribute to an Increased Risk of Atopic Dermatitis in Children// Dis Markers -2016; 2016: 1021942. Epub 2016 Apr 24
162. Sikandar A, Ullah N. Microarchitecture of the thymus gland, its age and diseae-associated morphological alterations, and possible means to prolong its physiological activity. Thymus, 2020. DOI: 10.5772/intechopen.88480
163. Sacide Pehlivan, Yasemin Oyaci [et al.] Interleukin-1 receptor antagonist (IL-1RA) and interleukin-4 (IL-4) variable number of tandem repeat polymorphisms in schizophrenia and bipolar disorder: an association study in Turkish population. Egyptian Journal of Medical Human Genetics (2022) 23:127
164. Singh RP, Hasan S, Sharma S, [et al.] Th17 cells in inflammation and autoimmunity. Autoimmun Rev. 2014;13:1174-81. doi: 10.1016/j. autrev. 2014.08.019
165. Sorokman T.V., Sokolnyk S.V. et al. Clinical features of acute respiratory viral infection sininfants with thymomegaly // Zdorov’e rebenka. 2016; (1): p.34-38.
166. Sovalkin, V.I. Pomogaylo Ye.G., Sabitova O.N. The role of tumor necrosis factor-α G-308A, interleukin-1β C-511T and interleukin-10 G-1082A gene polymorphism in the development of slowly resolved course of community-acquired pneumonia Byulleten sibirskoy meditsiny 2013;6: pp. 54-61.
167. Stagnieva I.V. [at.al] The role of cytokines in the diagnostics of inflammatory diseases of the upper respiratory tract. //doi: 1017116/rosrino 201725443-47
168. Stagnieva IV, Simbirtsev AS. Role of cytokine profile in manifestation of pain in rhinosinusitis. Cytosines and inflammation. 2015;14(4):29-34. (In Russ.)].
169. Statistical materials on the activities of healthcare institutions of the Republic of Uzbekistan in 2015. Tashkent 2016
170. Tengvall S. Interleukin-26 An Emerging Player in Host Defense and Inflammation / S. Tengvall, K.F. Che// Journal of Innate Immunity- 2016 p.15-22.
171. Umida I/ Zakirova [et al.] Comparative analysis of IL-8 cytokine polymorphism in inflammatory diseases of the bronchi in children of the Uzbek population// Journal of critical reviews ISSN Vol 7.p.2292-2297. ISSUE 17. 2020.
172. Esposito S.[et al.] Genetic polymorphisms and risk of recurrent wheezing in pediatric age// BMC Pulmonary Medicine 2014, 14:162 http://www.biomedcentral.com /1471-2466/14/162
173. Xie X.M. et al. interleukin-6 gene -174 G>C polymorphism andchronic obstructive pulmonary disease risk: // Genetics and Molecular Researc/- 2015. Vol.14 № 3. pp.8516-8525
174. Yakubova Z. Kh, Olimova K. S, Abdullaeva N. Sh. The role of thymomegalia in the health formation of early age children. Healthcare of Tajikistan. 2015; (1): 85-89. Russian
175. Yan F, Mo X, Liu J, Ye S. et al. Thymic function in the regulation of T-cells, and molecular mechanisms under lying the modulation of cytokines and stress signaling // Mol Med Rep. 2017 16(5):7175-7184.
176. Yang G, Chen J, Xu F, Bao Z, Yao Y, et al. (2014) Association between Tumor Necrosis Factor-a rs1800629 Polymorphism and Risk of Asthma: A MetaAnalysis. 9(6): e99962. doi:10.1371/journal.pone.0099962
177. Yi Hu, Linlin Wu [et. al] Association between cytokine gene polymorphisms and tuberculosis in a Chinese population in Shanghai: a case-control study BMC Immunology 2015 16:8 DOI 10.1186/s12865-015-0071-6
178. Zakirov I.I., Safina A.I. et al. Differential diagnosis of recurrent bronchitis in children. 2016; 61: 5: p.141-148 (in Russ).
179. Zhang T.C. The relationship between tumour necrosis factor-α gene polymorphism and susceptibility and clearance of the persistent hepatitis B virus infection in a Chinese population: a meta-analysis. Clinical Microbiology and Infection. Vol.20, Issue 3, 2014, pp. 227-234
180. Zhang- Ling, Yong-Hui Yang, Yan-Qin Liu [et al.] Genetic polymorphisms of the TNF-α-308G/A are associated with metabolic syndrome in asthmatic patients from Hebei province, China// Int J Clin Exp Pathol 2015;8(10):13739-13746 www.ijcep.com /ISSN:1936-2625/IJCEP0009466
181. Bakhronov Sh.S. Genetic markers of predisposition to the development of recurrent bronchitis in children with lymphatic-hypoplastic diathesis // New day in medicine 2021. 2. 34. P.260-265.
2. Akmalova G.M. and others. Genetic markers of predisposition to the development of relapses of the red plane of the oral mucosa // Experimental medicine, Kazan Medical Journal, 2016, volume 97, no.
3. pp.381-387. 3. Akparova A.Yu. and others. The role of the IL-4 and TNF-α cytokine genes in the development of predisposition to bronchial asthma and chronic obstructive pulmonary disease // Molecular genetic methods of research in medicine and biology. KarSMU. 2012. p.15-22.
4. Anokhina V.V., Neretina A.F., Kokoreva S.P. et al. Features of the course of acute respiratory diseases in children with respiratory diseases in children with an unfavorable premorbid background // Doctor. 2010, 27-30.
5. Antipkin Yu.G., Lapshin V.F. Recurrent bronchitis in children: modern issues of pathogenesis and diagnosis // Pediatrics No. 4 (43) 2017 p. 16
6. Akhverdieva T.B. Shuvalova Yu.V. Germasimova N.G. Features of the course and optimization of therapy for recurrent bronchitis in children // 2014 No. 6 p.56-66
7. Badyna O.S., Rovda Yu.I., et al. Sonometric parameters of the thymus gland in children in the first six months of life living in the Siberian region // Mother and Child in Kuzbass. 2014. p.153-158
8. Baike E.V., Urazov. O.I. Polymorphism of cytokine genes as a predisposition factor to the development of chronic otitis media // Pathological physiology and experimental therapy 2019 No. 1 p.4-14. 9. Balpanova G.T., Shortanbaev A.A., Talgatbekova D.Zh. Genetic markers of infectious diseases // Bulletin of KazNMU No. 4(1) 2013 p.100-102
10. Baranov A.A., Namozova-Baranova L.S. Federal clinical recommendations for providing medical care to children with acute bronchitis // M., 2015. 11 p.
11. Bakhodirova A.N., Alimova H.P., Rakhimova S.R. Principles for assessing the condition of children with broncho-obstructive syndrome in the emergency department // Bulletin of emergency medicine No. 3. Volume 12. 2019 p.26-27
12. Bodienkova G.M. The role of polymorphism and expression of individual cytokine genes in the formation of pathology // Modern advances. natural sciences. 2015. No. 1. c. 616-620
13. Boytsova E.A., Azimurodova G.O., Kosenkova T.V. Interleukin-4 Biological functions and clinical significance in the development of allergies // Preventive and clinical medicine No. 2(75) 2020 p.70-78
14. Vaganov P.D., Nikonova M.F., Yanovskaya et al. T-cell immunity in children with thymomegaly. Russian Medical Journal // 2017, 23 (6) p.298-302
15. Varyushina E.A. Pro-inflammatory cytokines in the regulation of inflammation and recovery processes // Abstract. St. Petersburg 2012. 16. Vozgoment O.V. On the role of lymphatic-hypoplastic diathesis in the fatal development of pathological processes in children and the criteria for its diagnosis // Difficult Patient No. 5, Volume 12. 2014 pp. 26-30
17. Volkov I. K. Differential diagnosis of broncho-obstructive syndrome in children // Emergency Medicine states. 2013. No.1. With. 125-128. 18. Volkova L.E., Rogalkaya S.V. Causes of perinatal death in children with thymus pathology // International Journal of Applied and Fundamental Research. 2013. No. 10-12. p.248-249
19. Vorobyova A.V. On the etiopathogenesis of acute bronchitis and bronchiolitis in children. Bulletin of new medical technologies // 2017. No. 4. P. 268-273.
20. Voropaeva Ya.V., Kuzmenko L.G. Prevalence of thymus diseases in children in the Russian Federation // Russian Bulletin of Perinatology and Pediatrics. 2012. No. 2. pp.99-103
21. Voropaeva Ya.V., Chibisov S.M. and others. Heliogeomagnetic situation in the first year of life of children with persistent thymic hyperplasia // The Journal of scientific articles “Health and Education Millennium”, 2015. No. 4 p. 262-265
22. Vychugzhanina E.Yu., Koledeva E.V. On the influence of thymic hyperplasia on the development of young children // Vyatka Medical Bulletin. 2015. No. 2. p.33-34
23. Geppe N.A., Kolosova N.G. Zaitseva O.V. and others. Diagnosis and therapy of bronchial asthma in preschool children. Place of use of inhaled glucocorticosteroids for bronchial asthma and croup // Russian Bulletin of Perinatology and Pediatrics. 2018. T. 63, No. 3. pp.124-132.
24. Gerasimova N. G., Akhverdieva T. B., Kondrashova Yu. V. et al. // Some aspects of the use of immunocorrective therapy for recurrent broncho-obstructive syndrome. Health and education in the 21st century. - 2016. No. 2. P. 568-570.
25. Guliev N.D., Ragimova N.D. Polymorphism of cytokine genes in non-congenital women with intrauterine infections \\ Russian Bulletin of Perinatology and Pediatrics, 2015 No. 6 p.42-47.
26. Guryeva, Larisa Lvovna Prediction of control of atopic bronchial asthma in childhood: abstract ... Doctor of Medical Sciences 01/14/08 Samara 2015
27. Danilko K.V., Bogdanova R.Z., Fatikhova A.I. and others. Polymorphism of cytokine genes in children with respiratory diseases // Modern problems of science and education. - 2015. -№6
28. Donetskova A.D., Nikonova M.F. and others. A new approach to the study of thymopoiesis in thymomegaly in children. Immunology. 2014; 4: p.204-208
29. Donetskova A.D., Nikonova M.F. and others. Features of T-lymphopoiesis in children with thymomegaly. Molecular diagnostics. Participating M: 2017 p.512-513
30. E.M. Kostina, B.A. Molotilov, O.A. Levashova et al. Study of polymorphism of the cytokine genes IL-4, IL-10, IL-17A and TNF-α in patients with infection-dependent bronchial asthma // Immunopathology. Infectology. 2013, No. 1, p. 53-58
31. Zaitseva O.V., Sitnikova E.P., Safina A.I. Comorbidity in pediatrics: is there a general solution // Effective pharmacotherapy. 2017. T. 3. No. 41. p.
32. Zaitseva O.V. Bronchitis in children, possibilities of herbal medicine // Russian Medical Journal. - 2013. -T. 21, no. 2. pp.96-102 33. Zykov M.V. et al. Study of the rs1800629 (G-308A) polymorphism of the TNF gene in patients with ST-segment elevation myocardial infarction. Russian Journal of Cardiology. http://dx.doi.org/10.15829/1560-4071-2014-10-13-18
34. Zykov M.V., Makeeva O.A. et al. Study of polymorphism rs 1800629 (G-308A) of the TNF gene in patients with myocardial infarction with ST segment elevation // Cardiogenetics, Russian Journal of Cardiology No. 10 (114) 2014
35. Kabbani M.S. Cell-mediated cytotoxicity (CD8 and CD16 phenotype) in the immune response (review) DOI:10.46742/2072-8840-2021-66-2-36-43,
36. Kaytmazova N.K. Dynamics of cytokine indicators in children with obstructive bronchitis when using immunomodulators in therapy http://dx.doi.org/10.26787/hydha-2686-6838-2019-21-12-39-44
37. Kazakova A.V., Uvarova E. .V., Limareva L.V. and others. Features of polymorphism of pro-inflammatory cytokine genes in girls predisposed to frequent respiratory diseases // Medical Genetics. Bulletin of the Russian State Medical University No. 6, 2019 p.61-66. 38. Kens E.V., Gnateiko O.Z., Lukyanenko N.S. Molecular genetic testing of single nucleotide polymorphism C-33T of the IL4 gene in children with repeated episodes of acute obstructive bronchitis // Medical Perspectives. 2018. p.67-71.
39. Kovalchuk L.V. Immunology: workshop: textbook. Manual / edited by. L.V. Kovalchuk, G.A. M.GEOTAR-Media 2014. p.174
40. Kosheleva I.V. The significance of serum levels and genetic characteristics of anti-inflammatory cytokines in patients with atopic dermatitis // Attending physician. 2019, No. 1, 53
42. Kuzmina L.P. Khotuleva A.G. Genetic polymorphism of anti-inflammatory cytokines in assessing the risk of development and prognosis of the course of occupational bronchopulmonary pathology. Collection of materials of the international scientific and practical conference. Moscow 2018 Volume 2 p.157-158
43. Lapshin V.F., Umanets T.R. Mucolytic therapy for children with recurrent bronchitis. Pathology pediatrics. 2014. 3(59):36-40; doi10.15574/pp.2014.59.36
44. Lastovka I.N. Features of the course of acute respiratory viral infections and meningococcal infection in young children with thymomegaly // Minsk, 2013. 21 p.
45. Lastovka I.N. Features of the course of acute respiratory infections in young children and thymomegaly // Protection of motherhood and childhood. 2013 p.20-24
46. Loginova N.P. Immunomorphological aspects of the structure of the thymus in children of the first year of life with congenital heart defects // Medical almanac. 2015. No. 2. p.112-116
47. Loskutov D.V., Khamitova R.Ya. Genetic component of chronic respiratory diseases among foundry workers // Hygiene and Sanitation. 2016.95. No. 7. p.623-626.
48. Lukashevich M.G., Surazakova T.N. Thymomegaly and the health status of children in the first year of life // Russian Bulletin of Perinatology and Pediatrics. 2016. T. 61, No. 4. P. 163.)
49. Maharramova S.G. Genetic polymorphism of cytokines in the development of respiratory diseases in children // DOI http: //dx.doi.org/10.5281/zenodo.1240483. Azerbaijan 2018 p.14-20.
50. Makarov S.Yu., Katilov A.V., Makarova O.I. Thymomegaly is a shadow of the past in the clinical practice of the present. LOOK FAHIVTSIA p.5-10 8(45)2015
51. Malanicheva T.G., Mozhgina S.S. and others. Local cytokine profile and cytological status in children with community-acquired pneumonia occurring against the background of reduced body resistance // Russian Bulletin of Perinotology and Pediatrics 2017: 62: (5) p. 139-143
52. Mirmanova N.A. Association of genetic polymorphism of the TNFα gene (G-308) with the formation of severe and complicated forms of influenza in children // Chita State Medical Academy Chita. Volume 5, No. 4 2013 p.30-34.
53. Moshchich A.P., Kalinichenko N.A. Rational correction of lymphatic-hypoplastic diathesis in the practice of a family doctor // Medicine of Ukraine No. 9-10. P.36-39. 2017
54. Mudrak D.A., Navolokin N.A. and others. Histological signs of enlargement of the thymus gland // Journal of Anatomy and Histology. 2020; 9(2): 46-52. doi: 10.18499/2225-7357-2020-9-2-46-52 9(2) pp.46-52.
55. Muhammadieva G.F., Kutlina T.G. and others. The role of polymorphic variants of TNF-α genes in the development of occupational bronchial asthma // Human Ecology No. 10. 2017. p. 34-38.
56. Minyailova N.N., Rovda Yu.I., Zinchuk S.F., Klimanova A.E., Stroeva V.P., Chernykh N.S. Aspects of the thymus gland in childhood (Part V). Hormonal and morphological relationships of the thymus with the neuroendocrine system and, in particular, with somatotropic hormone and insulin-like growth factor //Mother and Child in Kuzbass. 2022. No. 1(88). p.11-20.
57. Nasonov E.L. The role of interleukin 1β in the development of human diseases. Scientific and practical rheumatology. Moscow - 2018 No. 4 p.19-27.
58. Nevinsky A.B., Kramar L.V. and others. Modern approaches to the treatment and diagnosis of obstructive bronchitis in children // Medicine Bulletin 2015. No. 3 p. 46-47
59. Nesterenko Z.V. Recurrent bronchitis as a clinical variant of functional changes in the respiratory system in children // Pediatrician. - 2017. T.8-No.5 p.44-48.
60. Nesterenko, Z. V. Features of respiratory diseases in children with connective tissue dysplasia // Z. V. Nesterenko, A. A. Gritsai. Kharkov: 2014. 205 p.
61. Nikonova M.F. Vaganov P.D., Donetskova A.D. and others. The effect of tactivin therapy on T-lymphopoiesis in thymomegaly in young children with acute obstructive bronchitis // Russian Medical Journal 2017.p.18-20
62. Ovsyannikov D.Yu., Kravchuk D.A., Bolibok A.M. and others. Bronchial asthma is a difficult diagnosis in pediatrics // Clinical and emergency pediatrics 2016; 2: p.18-29.
63. Shaiderova I.G. Electromechanical activity of the heart and intracardiac hemodynamics in various forms of acute and recurrent bronchial pathology // Bulletin of Science and Practice. 2020. T. 6. No. 4. pp.112-117. https://doi.org/10.33619/2414-2948/53/13
64. Pavlenko V.A., Berezhansky P.V. Melnikova I.M. et al. Features of autonomic regulation in young children who have suffered acute obstructive bronchitis // Pulmonology of childhood: problems and solutions / ed. Yu.L Mizernitsky, A.D Tsaregorodtseva M. 2012. 254 p.
65. Pavlovskaya L.V., Boraeva T.T. Recurrent obstructive bronchitis as a risk factor for the development of bronchial asthma. Vladikavkaz Medical and Biological Bulletin. 2014; p78-82.
66. Pikuza O.I., Rizvanova F.F., Generalova E.V., Kravtsova O.A. Polymorphism of pro- and anti-inflammatory cytokine genes and acute bronchitis in children // Russian Bulletin of Perinatology and Pediatrics, 2017. No. 5. pp.136-138.
67. Pobedinskaya N.S., Ryvkin A.I., Glazova T.G., Reshetova T.G. Mechanisms of formation of high cough readiness in children with recurrent bronchitis // Pediatrics No. 2 (42) 2016 p.84-87.
68. Puzyreva L.V., Safonov A.D., Mordyk A.V. Respiratory diseases in HIV infection (REVIEW) // Journal of Infectology, Volume 8, No. 3., 2016. pp. 17-24.
69. Raisky D.V., Dzhumagaziev A.A., et al. Epidemiological features of acute bronchitis in Astrakhan children from 0 to 5 years of age from 2002 to 2012. Modern science and education // International scientific and practical conference. 2013 July 31, p.22-25
70. Rizvanova F.F., Pikuza O.I., Generalova E.V., Fayzullina R.A., Kravtsova O.A. Gene polymorphism and community-acquired pneumonia in children // Practical Medicine. 2018 Vol. 16, No. 8, pp. 70-73).
71. Rovda Yu.I., Minyailova N.N. and others. Aspects of the thymus gland (thymus) in childhood (part II) //Mother and Child in Kuzbass. 2021. No. 1(84). c. 4-23.
72. Rovda Yu.I., Vedernikova A.V., Minyailova N.N., Shabaldin A.V., Shmakova O.V., Chernykh N.S., Stroeva V.P. Aspects of the thymus gland in childhood (Part IV). Thymus and COVID-19 //Mother and Child in Kuzbass. 2021. No. 4(87). p.17-26
73. Rovda Yu.I., Shmulevich S.A., Shabaldin A.V. and others. Clinical and immunological characteristics of children in follow-up after surgery for congenital heart disease combined with forced thymusectomy // Pediatrics 2018. T. 97, No. 4. p. 50-58
74. Romanova E.N., Govorin A.V. Genetic polymorphism of TNF-a, IL-10, eNOS in patients with influenza A // H 1N1 complicated by pneumonia // Russia 2013. No. 3. With. 58-61.
75. Romantsev M.G., Melnikova I.Yu. and others. Respiratory diseases in frequently ill children // Doctor's Desk Reference. M.: GEOTAR-Med; 2017. 160.p.
76. Rubanenko O.A. Polymorphism of the genes interleukin 6, interleukin 10, superoxide dismutase and angiotensin converting enzyme and the risk of atrial fibrillation after cardiac surgery // Russian Cardiology No. 10 (138) 2016. pp. 37-42.
77. Rudenko K.A., Tuguz A.R. etc. The influence of polymorphism of the genes Il-17 (G197/197A), TNF-α (G308/308A), IL-6 (C174G) The influence of polymorphism of the genes IL-17 (G197/197A), TNF-α (G308 / 308A) , IL-6 (C174G) on spontaneous and in vitro stimulated production of the main proinflammatory cytokines in bronchial asthma // Immunology No. 2. 2014. p.92-94.
78. Savenkova N.D., Dzhumagaziev A.A., Bezrukova D.A., Raisky D.V. Markers of transient and persistent phenotypes of bronchial obstruction syndrome in children // DOI: 10.31550/1727-2378-2019-160-5-11-14
79. Savenkova N.D., Dzhumagaziev A.A., et al. Recurrent bronchitis in children: state of the problem // Astrakhan Medical Journal. 2014. No. 1. p.29-37.
80. Savenkova N.D., Dzhumangaziev A.A., Bezrukova D.A. Clinical and prognostic significance of broncho-obstructive syndrome phenotypes in the development of bronchial asthma in children // Astrakhan Medical Journal No. 2, 2019. pp. 51-59.
81. Samorodnova E.A., Fayzullina R.A. and others. Pathogenetic significance of membrane and metabolic disorders in bronchitis in children // DOI: 10.31550/1727-2378-2021-20-10-18-24
82. Sartaeva G.Sh., Iseva A.G. and others. The special role of tumor necrosis factor-alpha in the anti-tuberculosis response. Bulletin of KazNMU No. 4. 2018 p.69-73
83. Seliverstova E.N. Sergienko D.F., Bashkina. O.A. Clinical, diagnostic and prognostic significance of the IL-4 gene in the recurrent course of bronchial obstruction syndrome in children // Astrakhan Medical Journal No. 2, 2019 p.59-66.
84. Sereda E.V. Etiology and innovative approaches in the treatment of acute and chronic infectious and inflammatory bronchopulmonary diseases in children // Issues of modern pediatrics. -2011. Volume 10, No. 3. p.124-130.
85. Silantyeva I.V., Rovda Yu.I. and others. Sonometric parameters of the thymus gland in healthy and sick children of the first two years of life // Siberian Medical Journal. 2012. T. 27, No. 1. p. 103-106.)
86. Simbirtsev A.S. Immunopharmacological aspects of the cytokine system // Bulletin of Siberian Medicine // 2019 No. 1 p.84-95.
87. Simbirtsev A.S. Cytokines in the pathogenesis of human infectious diseases. // Medical academic journal 2013 No. 3 p. 18-41.
88. Smirnova A.Yu. Gnoevykh V.V. and others. Genetic aspects of multifactorial broncho-obstructive diseases // Ulyanovsk Medical and Biological Journal No. 1. 2014. p.8-17.
89. Smiyan A.I., Romanova T.A. and co-author. Features of the population composition of peripheral blood lymphocytes and immunoglobulins in children with acute obstructive bronchitis against the background of thymomegaly // Scientific bulletins of BelSU. Series Medicine Pharmacy 2014 No. 11 (182). p.37-41
90. Sorokman T.V., Sokolnik S.V., et al. Features of the course of acute respiratory viral infections in young children with thymomegaly // Child's Health 2016. No. 1. P. 34-38
91. Stashkevich D.S. Topical issues of immunology: cytokine system, biological significance, genetic polymorphism, determination methods // Textbook. Chelyabinsk 2016. 82 p.
92. Tatochenko V.K. Respiratory diseases in children: V.K. Tatochenko. Medicine, 2012. p.480.
93. Tatochenko V.K. Respiratory diseases in children: A practical guide. 2019.p.300
94. Trushina E.Yu., Kostina E.M., Molotilov B.A., Tipikin V.A. Baranova N.I. The role of cytokines IL-4, IL-6, IL-8, IL-10 in the immunopathogenesis of chronic obstructive pulmonary disease // Medical Immunology. 2019. T. 21. No. 1. c.89-98
95. Trushina E.Yu., Kostina E.M., Baranova N.I., Tipikin V.A. The role of cytokines as molecular markers of inflammation in non-allergic bronchial asthma // Modern problems of science and education. 2018. No. 4
96. Uzakbaev K. A. Acute bronchopulmonary pathology in children with congenital heart defects // International scientific and practical conference. Bishkek, 2016. pp. 89-90.
97. Fayzieva U.G. Features of the IL-1 and IL-4 genes in community-acquired pneumonia in children. Eurasian Bulletin of Pediatrics 3(10) 2021 p.40-43
98. Furman E.G., Mazunina E.S., Boytsova E.V., Ovsyannikov D.Yu. Prolonged bacterial bronchitis in children is a “new” “old” disease. Pediatrics. 2017; 96(2): pp.136-144.
99. Khaitov R.M. Immunology: textbook for universities / R.M. Khaitov. -2nd ed. processed additional GEOTAR-Media 2013. 521 p.
100. Kholodova I.N., Zakharova I.N. Returning to the past, or let's talk about the human constitution. Concilium Modicum. Pediatrics. 2016; 1: p.20-23.
101. Khotko E.A., Taganovich A.D. Polymorphism of receptor genes and their ligands in chronic obstructive pulmonary disease // Medical Journal. Belarus 2016 No. 3. pp. 36-42.
102. Chemodanov V.V., Krasnova E.E., Moshkova A.V. Features of bronchitis in combination with various pathologies in young children // Attending physician. 2021; 1 (24): pp.16-19.
103. Chirkova N.V., Baldina N.S., Dulkin L.A. Features of the course of recurrent obstructive bronchitis and community-acquired pneumonia in children with gastroesophageal reflux // Pediatrics (Appendix to the journal). 2017; 3: pp.101–104.
104. Churina E.G. Urazova O.I., Novitsky V.V. et al., Functional polymorphism of pro-inflammatory cytokine genes in pulmonary tuberculosis // Medical Immunology 2019 T. 21, No. 1, pp. 149-156
105. Shabalov N.P., Arsentiev V.G., Ivanova N.A. and others. Age-specific constitutional anomalies and diathesis. Pediatrics 2016; 2: pp.82-85.
106. Shamsiev A.M., Yusupov Sh.A., Mukhamadieva L.A., Yuldashev B.A. Features of changes in immunological parameters in children with chronic bronchitis. Scientific and practical journal // Bulletin of Nankov Doslidzheni” Ternopil No. 4 (85) 2016 p. 26-29.
107. Shamsiev A.M., Yusupov Sh.A., Mukhamadieva L.A., Yuldashev B.A. The state of the immune status in children with chronic bronchitis. Periodic information and analytical journal of the Chelyabinsk Regional Children's Clinical Hospital “Pediatric Bulletin of the Southern Urals” 2017, No. 1 p. 84-89.
108. Shields M.D., Doherty G.M. Chronic cough in children // Clinical and emergency pediatrics. 2015; 1: p.11-20.
109. Shuvalova Yu.V. Clinical and laboratory effectiveness of polyoxidonium in complex therapy of recurrent bronchial obstruction syndrome in children // Modern problems of science and education. 2013. No. 2. www.science-education.ru/ 108-8968.
110. Shcherbak V.A. Diathesis and constitutional anomalies in children //Siberian Medical Education 2014. 3. p.75-79.
111. Yakovenko M.P. Morbidity of children born with low and extremely low body weight with developed bronchopulmonary dysplasia // Attending physician - 2017. No. 11. P. 52-56.
112. Yakubova Z.Kh., Olimova K.S., Abdullaeva N.Sh. The role of thymomegaly in the formation of the health status of young children // Healthcare of Tajikistan. 2015. No. 1. P. 85-89
113. Yarilin A.A., Donetskova A.D. T cells are recent emigrants from the thymus. Immunology. 2012; 33 (6): 326-34.
114. Yarovaya Yu. A., Lozovskaya M. E., Vasilyeva E. B. et al. Constitutional features in children with tuberculosis infection // Tuberculosis and Lung Diseases. DOI: 10.21292/2075-1230-2017-95-4¬ 20-25
115. Al-Mohaya M.A., Al-Harthi F., Arfin M., Al-Asmari A. TNF-α, TNF-β and IL-10 gene polymorphism and association with oral lichen planus risk in Saudi patients. J. Appl. Oral Sci.2015; 23(3):295-301
116. Arsanova H.I., Kasymova Y.B., Bashkina O.A. Recurrent bronchitis in children:state of the problem. Archiveseuromedica 2018. Vol.8 No. 2. pp.67-68.
117. Ayhan G, Tas D, Yilmaz I, Okutan O, Demirer E, Ayten O, Kartaloglu Z. Relation between inflammatory cytokine levels in serum and bronchoalveolar lavage fluid and gene polymorphism in young adult patients with bronchiectasis. J Thorac Dis 2014;6(6):684-693. doi: 10.3978/j.issn.2072-1439.2014.04.14
118. Babusikova E. [et al.] Association of Gene Polymorphisms in Interleukin 6 in Infantile Bronchial Asthma. Subscribe to this journal July 2017. p.381-386
119. Bohmwald K, Gálvez NS, Canedo-Marroquín G, Pizarro-Ortega MS, Andrade-Parra C, Gómez-Santander F and Kalergis AM (2019). 10: 452. DOI: 10.3389/fimmu.2019.00452
120. Chkhartishvili E. Thymomegaly and recurrent disease episodes in childrrin ESPID 2018. May 28 -Jun 2. https:// www. Morressier.com/article/thymomegaly-recurrent -episodes-children/ ad 774e0d462b80296ca6d06
121. Cowan J.E., Takahama Y. et al. Postnatal involution and counter-involution of the thymus. Front Immunol. 897. DOI: 10.3389/fimmu.2020.00897
122. Dawid S. [et al.] The signifcace of IL-1β+3953 C>T, IL-6 174 G>C and 696 G>A, TNF-α-308 G>A gene polymorphisms and 86 bp variable number tandem repeats et polymorphism of IL-1RN bronchopulmonary dysplasia in infantis born before 32 weeks of gestation /Cent Eur J Immunol. 2017: 42(3): p.287-293
123. Dinarello C.A. Overview of the IL-1 family in innate inflammation and acquired immunity// Immunol Rev. 2018 January;281(1): 8-27/ doi:10.1111/imr.12621.
124. Furkat Shamsiev [et.al] TNFα polymorphism (-308G>A) in children with chronic bronchitis// European Journal of Molecular et Clinical Medicine ISSN 2515-8260 Volume 7, Issue 2, pp. 2515-2520. 2020
125. Rincon M. et al., Role of IL-6 in Asthma and Other Inflammatory Pulmonary Diseases. Int J Biol Sci 2012; 8(9):1281-1290. doi:10.7150/ijbs.4874. Available from https:// www.ijbs.com / v 08 p.1281.htm
126. Gandhi F Pavon-Romero [at.al]. Single nucleotide polymorphisms in TNF are associated with susceptibility to aspirin-exacerbated respiratory disease but not to cytokine levels: a study in Mexican mestizo population. Biomark. Med 2017 11(12) 1047-1055
127. Gul K.A., Sonerud T, Fjærli H.O., Nakstad B, Abrahamsen T.G, Inchley C.S. Thymus activity measured by T-cell receptor excision circles in patients with different severities of respiratory syncytial virus infection BMCInfectDis. 2017; 17: 18. DOI:10.1186/s12879-016-2148-0
128. Haiyan Mu, Qingqing Zheng. IL-10-1082 A/G polymorphism is related with the risk and clinical characteristics of acute kidney injury: a case-control study. BMC Nephrology 2021. pp.1-6
129. Henan Madani. Hanaa I. Rady. Association of cytokine genes polymorphisms and the response to corticosteroid therapy in children with idiopathic nephrotic syndrome: A pilot study in Egypt/ International Research Journal of Medicine and Medical Sciences Vol.2(4), pp. 84-90, December 2014
130. Huang H, Nie W, Qian J [at al.] Effects of TNF-α Polymorphisms on Asthma. Esmon Publicidad.J Investig Allergol Clin Immunol 2014; Vol. 24(6): 406-417
131. HuGE Navigator (2013). Available at: http://www. Huge navigator. net/HuGE Navigator/ gene Prospector (accessed June 2013).
132. Hsu H.J., Yang Y.H., Shieh T.Y. et al. Role of cytokine gene (interferon-y, transformimg growth factor-β1, tumor necrosis factor-α, interleukin-6, and interleukin-10) polymorphismus in the risk of oral precancerous lesions in Taiwanese. Kaohsiung J. Med. Sci. 2014; 30 (11): 551-558
133. Interleukin-6 gene –174 G>C polymorphism and chronic obstructive pulmonary disease risk: a meta-analysis / X. M. Xie [et al.] // Genetics and Molecular Researc. - 2015.- Vol. 14, № 3. P. 8516-8525. 2015. №3 с.46-47
134. Ivanova N. A. Recurrent bronchial obstruction and asthma in children during the first five years of life. Russian Bulletin of Prenotology and Pediatrics 2016; (in Russ). DOI: 10.21508/1027-4065-2016-61-5-64-69
135. Ji-Hong Zhang, Mei Zhang, Ya-Nan Wang Correlation between IL-4 and IL-13 gene polymorphisms and asthma in Uygur children in Xinjiang DOI:10.3892/etm.2018.7096 pp.1374-1382.2019
136. Jin X., Wang J., Zhu L. [et al.] Association between -308 G/A polymorphism in TNF-α gene and lichen planus: a meta- analysis. J. Dermatol. Sci. 2012; 68; 127-134.
137. Jiang P, Yue Y-X, Hong Y, Xie Y, Gao X, Gu C-K, Hao H-J, Qin Y, Ding X-J, Song M, Li H-F and Zhang X (2018) IL-4Rα Polymorphism Is Associated With Myasthenia Gravis in Chinese Han Population. Front. Neurol. 9:529. doi: 10.3389/fneur.2018.00529
138. Kellogg C, Equills O. The role of the thymus in COVID-19 disease severity: implications for antibody treatment and immunization. Hum Vaccin Immunother. 2020.1-6. DOI: 10.1080/21645515.2020.1818519.
139. Kuzmenko L.G., Kiseleva N. M. Contemporary on the role of thymus in living organisms and its participation in the vaccinal process in children of young age. Clinical Pathophysiology. 2016:3(22): 104-114
140. Kuzmenko L.G., Smyslova Z.V, Kiseleva N.M, Bystrova O.V, Agarval R.K. To the question of the thymus, associated terminology, and health status of children with a large thymus. J of Scientific Articles Health and Education in the Education in the XXI Century. 2015; 17(4): 97-107.
141. Kurtukov E.A., RaginoYu.I. Potential biochemical marker sof chronic bronchitis. Bulletin of Siberian Medicine. 2021; 20 (2): 148–159. https://doi.org/10.20538/1682-0363-2021-2-148-159.
142. Lu R., Zhang J., Sun W. et al. Inflammation-related cytokines in oral lichen planus: an overview. J. Oral Pathol. Med. 2015; 44: 1-14
143. Luciano B Silva, Alexaandrino P [et al.] // The role of TNFα as a Proinflammatory cytokine in pathological processes. The Open Dentistry Journal.DOI: 10.2174/1874210601913010332, 2019, 13, 332-338
144. Lukashevich M.G., Surazakova T.N. Thymomegaly and the state of health of children in the first year of life. Russian Bulletin of perinatology and pediatrics. 2016; 61(4): 163.
145. Mayyada F Darweesh [at ol.]. The impact of genetic variation at TNF- α 308G/A on their serum production and severity of asthma disease// Journal of Physics 2019 pp.1-8
146. María Luisa Reigada-Rivera, Catalina Sanz Lozano [et ol.]. Polymorphisms in Human IL4, IL10, and TNF Genes Are Associated with an Increased Risk of Developing NSAID-Exacerbated Respiratory Disease Genes 2022, 13, 605. https://doi.org/10.3390/genes13040605 h
147. Mizernitsky Yu.L. Pathogenetic rationale for the use of montelukast (Singlon) in acute respiratory viral infections with broncho-obstructive syndrome in children of early and preschool age. Ros Vestn Perinatoli Pediatr 2020; 65:(6): 129-132 (inRuss).
148. Nataliia Lukianenko [at.al] Finding a molecular genetic marker for the incidence of recurrent episodes of acute obstructive bronchitis in children// Journal of medicine and life. Pp695-699. 2021
149. Nesterenko Z.V. Recurrent bronchitis as a phenotypic variant of acute bronchitis in children. Ukraїnski jmedichnij vіsnik 2012; 15: p.121-123.
150. Onur Ismi [et. al]. TNF-α and IL-1β Cytokine gene polymorphism in patients with nasal polyposis. Turk arch Otorhinolaryngology 2017: pp.51-55
151. Patwari P.P. [et al.] Interleukin-1 receptor antagonist intron 2 variable number of tandem repeats polymorphism and respiratory failure in children with community-acquired pneumonia // Pediatr. Crit Care Med. 2008. Vol.9. №6 pp.553-559.
152. Pavón-Romero, G.F.; Reséndiz-Hernández, J.M. [et ol.]. Single nucleotide polymorphisms in TNF are associated with susceptibility to aspirin-exacerbated respiratory disease but not to cytokine levels: A study in Mexican mestizo population. Biomark. Med. 2017, 11, 1047–1055. [CrossRef] [PubMed]
153. Polyakov V.V., Senatorova A.S. The clinical significance of endothelial dysfunction in children with recurrent obstructive bronchitis and bronchial asthma. Mezhdunarodnij meditsinskij zhurnal 2012; 2: 32-36.
154. Petrova A.I., GaymolenkoI.N., Tereshkov P.P. Clinical and immunological markers of acute obstructive bronchitis in preschool children. Siberian medical review. 2019;(6):32-36. (In= Russ.) https://doi.org/10.20333/2500136-2019-6-32-36.
155. Qi Xiao [at.al] Three polymorphisms of tumor necrosis factor-alpha and hepatitis B virus related hepatocellular carcinoma. Medicine 2016 (95:50 (e5609).
156. Rakhmanova L.K., Savenkova N.D., Iskandarova I.R. Immune-hematological risks of progression of chronic kidney disease in children with lymphatic diathesis. // journal of Xi`an University, Natural Science Edition. Vol. 16. Pp297-311. 2018
157. Resul Kahraman [at al.] Evaluation of TNF alpha G308A promoter gene polymorphism and serum TNF alpha levels in patients with inflammatory bowel disease in Turkish population. Medicine Science 2019: 8(4): 1006-10.
158. Sanchez-Dominguez [et al.] (2014) The Tumor Necrosis Factor α (-308 A/G) Polymorphism Is Associated with Cystic Fibrosis in Mexican Patients. 9(3): e90945. https://doi.org/10.1371/journal.pone.0090945
159. Savenkova N.D., Dzhumangaziev A.A. et al. Rehabilitation of children with recurrent bronchitis using a nov-invasive apparatus of microwave exposure. [Human Ecology]. 2017, 12, pp. 53-58.
160. Schett G, Dayer J-M, Manger B. Interleukin-1 function and role in rheumatic disease. Nat Rev Rheumatol. 2016 Jan;12(1):14-24. doi: 10.1038/nrrheum.2016.166
161. Shang H., Cao X.L., Wan Y.J., Meng J., Guo L.H IL-4 Gene Polymorphism May Contribute to an Increased Risk of Atopic Dermatitis in Children// Dis Markers -2016; 2016: 1021942. Epub 2016 Apr 24
162. Sikandar A, Ullah N. Microarchitecture of the thymus gland, its age and diseae-associated morphological alterations, and possible means to prolong its physiological activity. Thymus, 2020. DOI: 10.5772/intechopen.88480
163. Sacide Pehlivan, Yasemin Oyaci [et al.] Interleukin-1 receptor antagonist (IL-1RA) and interleukin-4 (IL-4) variable number of tandem repeat polymorphisms in schizophrenia and bipolar disorder: an association study in Turkish population. Egyptian Journal of Medical Human Genetics (2022) 23:127
164. Singh RP, Hasan S, Sharma S, [et al.] Th17 cells in inflammation and autoimmunity. Autoimmun Rev. 2014;13:1174-81. doi: 10.1016/j. autrev. 2014.08.019
165. Sorokman T.V., Sokolnyk S.V. et al. Clinical features of acute respiratory viral infection sininfants with thymomegaly // Zdorov’e rebenka. 2016; (1): p.34-38.
166. Sovalkin, V.I. Pomogaylo Ye.G., Sabitova O.N. The role of tumor necrosis factor-α G-308A, interleukin-1β C-511T and interleukin-10 G-1082A gene polymorphism in the development of slowly resolved course of community-acquired pneumonia Byulleten sibirskoy meditsiny 2013;6: pp. 54-61.
167. Stagnieva I.V. [at.al] The role of cytokines in the diagnostics of inflammatory diseases of the upper respiratory tract. //doi: 1017116/rosrino 201725443-47
168. Stagnieva IV, Simbirtsev AS. Role of cytokine profile in manifestation of pain in rhinosinusitis. Cytosines and inflammation. 2015;14(4):29-34. (In Russ.)].
169. Statistical materials on the activities of healthcare institutions of the Republic of Uzbekistan in 2015. Tashkent 2016
170. Tengvall S. Interleukin-26 An Emerging Player in Host Defense and Inflammation / S. Tengvall, K.F. Che// Journal of Innate Immunity- 2016 p.15-22.
171. Umida I/ Zakirova [et al.] Comparative analysis of IL-8 cytokine polymorphism in inflammatory diseases of the bronchi in children of the Uzbek population// Journal of critical reviews ISSN Vol 7.p.2292-2297. ISSUE 17. 2020.
172. Esposito S.[et al.] Genetic polymorphisms and risk of recurrent wheezing in pediatric age// BMC Pulmonary Medicine 2014, 14:162 http://www.biomedcentral.com /1471-2466/14/162
173. Xie X.M. et al. interleukin-6 gene -174 G>C polymorphism andchronic obstructive pulmonary disease risk: // Genetics and Molecular Researc/- 2015. Vol.14 № 3. pp.8516-8525
174. Yakubova Z. Kh, Olimova K. S, Abdullaeva N. Sh. The role of thymomegalia in the health formation of early age children. Healthcare of Tajikistan. 2015; (1): 85-89. Russian
175. Yan F, Mo X, Liu J, Ye S. et al. Thymic function in the regulation of T-cells, and molecular mechanisms under lying the modulation of cytokines and stress signaling // Mol Med Rep. 2017 16(5):7175-7184.
176. Yang G, Chen J, Xu F, Bao Z, Yao Y, et al. (2014) Association between Tumor Necrosis Factor-a rs1800629 Polymorphism and Risk of Asthma: A MetaAnalysis. 9(6): e99962. doi:10.1371/journal.pone.0099962
177. Yi Hu, Linlin Wu [et. al] Association between cytokine gene polymorphisms and tuberculosis in a Chinese population in Shanghai: a case-control study BMC Immunology 2015 16:8 DOI 10.1186/s12865-015-0071-6
178. Zakirov I.I., Safina A.I. et al. Differential diagnosis of recurrent bronchitis in children. 2016; 61: 5: p.141-148 (in Russ).
179. Zhang T.C. The relationship between tumour necrosis factor-α gene polymorphism and susceptibility and clearance of the persistent hepatitis B virus infection in a Chinese population: a meta-analysis. Clinical Microbiology and Infection. Vol.20, Issue 3, 2014, pp. 227-234
180. Zhang- Ling, Yong-Hui Yang, Yan-Qin Liu [et al.] Genetic polymorphisms of the TNF-α-308G/A are associated with metabolic syndrome in asthmatic patients from Hebei province, China// Int J Clin Exp Pathol 2015;8(10):13739-13746 www.ijcep.com /ISSN:1936-2625/IJCEP0009466
181. Bakhronov Sh.S. Genetic markers of predisposition to the development of recurrent bronchitis in children with lymphatic-hypoplastic diathesis // New day in medicine 2021. 2. 34. P.260-265.